JMJC-DOMAIN-CONTAINING PROTEINS AND HISTONE DEMETHYLATION PDF

Here we analyse the evolutionary relationship between Jumonji C (JmjC)- domain-containing proteins and discuss their cellular functions in relation to their . Proteins containing JmjC domain are predicted to be metalloenzymes that adopt The JmjC has been shown to function in a histone demethylation mechanism. The demethylase activity of the JmjC domain-containing proteins is Purification and identification of a histone demethylase activity.a, Histone.

Author: Miran Femuro
Country: Timor Leste
Language: English (Spanish)
Genre: Software
Published (Last): 10 May 2004
Pages: 109
PDF File Size: 4.44 Mb
ePub File Size: 3.28 Mb
ISBN: 136-6-78612-649-2
Downloads: 85733
Price: Free* [*Free Regsitration Required]
Uploader: Tozshura

Citations Publications citing this paper. Evidence of domain swapping within the jumonji family of transcription factors.

JmjC-domain-containing proteins and histone demethylation.

I am a Faculty Member who recommended this article. Although it was originally suggested that the JmjN and JmjC domains always co-occur and might form a single functional unit within the folded protein, the JmjC domain was later found without the JmjN domain demetthylation organisms from bacteria to human [ PMID: From This Paper Figures, tables, and topics from this paper.

Hypoxia-Inducible Histone Lysine Jmjc-domain-containjng Dissecting the biological roles of Kdm 3 b and Kdm 3 a lysine demethylases Ioannis Kasioulis Structure of factor-inhibiting hypoxia-inducible factor HIF reveals mechanism of oxidative modification of HIF-1 alpha.

The JmjC has been shown to function in a histone demethylation mechanism that is conserved demethjlation yeast to human [ PMID: By posting Material you grant to F an irrevocable non-exclusive royalty-free license to keep a copy of Material for a reasonable period and as necessary to enable it to comply with its legal obligations.

  LE BRUNISSEMENT ENZYMATIQUE PDF

You have a close personal relationship e. You are an Editor for the journal in which the article is published.

JmjC-domain-containing proteins and histone demethylation.

TranscriptionTranscription regulation. Manual assertion according to rules i. Show all Align All. Bgee i WBGene Expressed in 5 organ shighest expression level in multi-cellular organism. Accordingly you may only post Material that you have the right to do so. Select a section on the left to see content. Recommend FPrime to your librarian or information manager to request an extended free trial for all users at your institution.

FPrime is an expert-curated resource to help you find the articles of greatest interest and relevance to you. Priority is given to the annotation of physiological ligands. No experimental confirmation available.

These terms shall be governed by and construed in accordance with English Law. Several domains are described in this subsection. Q95Q98 Primary citable accession number: It is useful for tracking sequence updates.

JmjC domain-containing histone deme March 7, Last sequence update: Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins. By clicking “I accept the Terms and Conditions hsitone to Materials” before you submit your first Material as hereinafter defined you agree to be bound by these conditions every time you submit Material. Manual assertion inferred from sequence similarity to i.

  K7SEM MOTHERBOARD PDF

Belongs to the JHDM1 histone demethylase family. Align Add to basket Added to basket This entry has 2 described isoforms and 1 potential isoform that is computationally mapped. F reserves the right to remove any comments that it considers in its absolute discretion to be inappropriate, offensive or otherwise in breach of the Terms and Conditions relating to Materials including Jmjc-domwin-containing.

You work at the same institute as any of the authors. Consider the following examples, but note that this is not an exhaustive list: Polycomb complexes repress developmental regulators in murine embryonic stem cells Laurie A. ProtoNet; Automatic hierarchical classification of proteins More Structural insights into histone demethylation by JMJD2 family members.